Melanomas that develop within the eye inhibit lymphocyte proliferation

Identification of the predominant proteins in uterine fluids of unilaterally pregnant ewes that inhibit lymphocyte proliferation.

Uterine fluid from unilaterally pregnant ewes contains activity inhibitory to lymphocyte proliferation. The molecules responsible for this activity may thereby regulate uterine immune responses during pregnancy. The purpose of the experiment described here was to identify the major protein in uterine fluid responsible for this activity. When uterine fluid was fractionated by a combination of ca...

Follicular dendritic cells inhibit human B-lymphocyte proliferation.

In germinal centers, B lymphocytes are intimately associated with follicular dendritic cells (FDCs). It has been hypothesized that FDCs are involved in the regulation of B-cell growth and differentiation through cell-cell interactions. In this study, highly enriched preparations of FDCs were isolated by cell sorting using the FDC restricted monoclonal antibody DRC-1. When irradiated FDCs were c...

Lymphocyte Progenitor Cells Causes Thymic Cell Proliferation Arrest within Intrathymic

Neutrophil products that inhibit cell proliferation: relation to granulocytic "chalone".

Various investigators have proposed the existence of a “chalone” or product of mature granulocytes which inhibits the replication of granulocytic progenitors in a tissue-specific, species-nonspecific regulatory system. We tested this system utilizing purified populations of human leukocytes and a variety of proliferating target cell populations. Granulocyte-conditioned medium potently inhibited...

Factors that enhance and inhibit learning within email discussion groups

A study examined the characteristics of the learning process when it is facilitated by computer-mediated communication in nonformal learning contexts. In this paper, learning is defined as the transformation of experience through reflection, conceptualization, and action. Such experiential learning often occurs in dialogue with others. "Learning communities" are communities of practice--problem...